Isolation and characterization of a dihydrostilbene from the aerial parts of Indigofera conferta

Maryam Isah; Asmau N. Hamza; Nkiruka Theresa Nnadozie; Edward Ayakeme Bebe; Nasir Tajuddeen; Aliyu M. Musa

doi:10.61298/rans.2026.4.1.246

Authors

Maryam Isah
[email protected]

Department of Science Laboratory Technology, Federal University of Lafia, Nasarawa, Nigeria
Asmau N. Hamza
Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
Nkiruka Theresa Nnadozie
Department of Chemistry, Federal University of Lafia, Nigeria
Edward Ayakeme Bebe
Department of Chemistry, Federal University of Lafia, Nigeria
Nasir Tajuddeen
Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria
Aliyu M. Musa
Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria

Keywords:

Indigofera conferta, Isolation, Characterization, Dihydrostilbene

Abstract

Indigofera conferta, an annual herb widely distributed in northeastern and western Nigeria, is used ethnomedicinally to treat inflammation, pain, sore feet, and snakebite. Despite these uses, the phytochemical constituents of this species remain underexplored. The chloroform fraction of the methanol extract of the aerial parts of I. conferta was separated by silica gel column chromatography to afford a compound. The structure of the compound was elucidated using UV, FT-IR, one-dimensional and two-dimensional NMR (¹H, ¹³C, HSQC, and HMBC) spectroscopy and comparison with previously reported literature data. The compound was assigned as 3,5-dimethoxy-4'-O-(2,3-dihydroxy-3-methylbutyl)-dihydrostilbene. This report documents the first isolation of this compound from I. conferta and contributes to the phytochemical and chemotaxonomic knowledge of the genus Indigofera.

Dimensions

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